Polymer stability study

We provide support of stability test, evaluation, and applications for polymer based on our extensive experience and knowledge.

We are contract research organization for a project commissioned by Ministry of Economy, Trade and Industry / 2016 fiscal chemical safety measures (research and study on evaluation method of the polymer).

Correspondence for CSCL / Polymer Flow Scheme

We have over 1,000 extensive experience in the Polymer Flow Scheme^*1 compliance with the Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law, CSCL).
We also cover technical consulting and consultations with the authority for the application, as well as applications for CSCL and polymers of low concern.

*1：In the polymer flow scheme, the following tests are performed

Stability test in acid and alkali
Solubility test in water and organic solvents
Molecular weight distribution measurement (GPC, etc.)

Application of CSCL for Polymer Containing 1% or More of Low-Molecular Weight Components

CSCL was amended in 2010 to enable applications using results of polymer flow schemes and bioaccumulation in fish for polymer^*2 that contain high levels of low-molecular weight components.

In addition to the polymer flow scheme, we provide total support for bioaccumulation in fish and final applications.

*2：Polymers which the content of components with molecular weights of less than 1,000 is 1% or more are applicable.

Correspondence for overseas legal regulations

Applications for polymer to chemical substances control law in other countries require results of molecular weight measurement and stability test in acid and alkali.

We propose data collection plan tailored to the country of application, and also support application to each country, maintenance of registration after completion of the application.

Major Applications Country and Required Information for Polymer

Country	Applicable Law	Test items
China	Measures for the Environmental Management Registration of New Chemical Substances Record (Polymer)	Molecular weight distribution measurement (GPC)
China	Measures for the Environmental Management Registration of New Chemical Substances Simplified Registration Regular Registration	Molecular weight distribution measurement (GPC) (Solubility test in water and organic solvents) (Stability test for acid and alkali)
Korea	Act on Registration and Evaluation of Chemicals (K-REACH) Application for confirmation of exemption from registration of polymer	Molecular weight distribution measurement (GPC) Residual monomer analysis
	Act on Registration and Evaluation of Chemicals (K-REACH) Application for registration of polymer	Stability test against acid and alkali Molecular weight distribution measurement (GPC) Residual monomer analysis
	Occupational Safety and Health Act (K-OSHA) Application for confirmation of exemption from registration of polymer	Molecular weight distribution measurement (GPC)
	Occupational Safety and Health Act (K-OSHA) Application for registration of polymer	Stability test against acid and alkali Molecular weight distribution measurement (GPC) Residual monomer analysis
Taiwan	Toxic and Concerned Chemical Substances Control Act Occupational Safety and Health Act Prior confirmation for polymer of low concern	Molecular weight distribution measurement (GPC) (Stability test for acid and alkali)
Taiwan	Toxic and Concerned Chemical Substances Control Act Occupational Safety and Health Act Small quantity registration Simplified registration Standard registration	Molecular weight distribution measurement (GPC) IR or NMR measurement ※Depending on the registration category, it is necessary to separately perform a physical property measurement test, a toxicity test, and an ecotoxicity test.

Sample check service

We conduct screening checks for the stability and solubility of polymer for applications compliance with various legal regulations.
For example, the stability and solubility of multiple samples in the early stages of development verify with minimal test configurations as desired.
We provide support in the product development according to the launch project, such as proposing an application method that matches the test results.

Please feel free to contact us if you have any requests.

Our Environmental, Health and Safety Assessment Center^*3 is a contract research organization for a project commissioned by Ministry of Economy, Trade and Industry / 2016 fiscal chemical safety measures (research and study on evaluation method of the polymer) (project completed in March 2017).　In this project, we examined the applicability of the 2% rule^※ in Japan, the survey of evaluation methods for polymer in other countries, and the rationalization of polymer flow schemes.

*In other countries, it is generally accepted that the addition of 2% of different monomers to a polymer is regarded as the same compound.

Download Report (Approx. 98MB)

*3：We succeed to the environmental risk assessment business of LSI Medience Corporation on July 1, 2021.